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Gene : SELENOI Homo sapiens

Name  ? selenoprotein I Cytological Location  2p23.3
Brief Description  selenoprotein I
Description  The multi-pass transmembrane protein encoded by this gene belongs to the CDP-alcohol phosphatidyltransferase class-I family. It catalyzes the transfer of phosphoethanolamine from CDP-ethanolamine to diacylglycerol to produce phosphatidylethanolamine, which is involved in the formation and maintenance of vesicular membranes, regulation of lipid metabolism, and protein folding. This protein is a selenoprotein, containing the rare selenocysteine (Sec) amino acid at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2016]
  • synonyms:
  • SEPI,
  • HGNC:29361,
  • ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific),
  • EPT1,
  • OTTHUMG00000151931,
  • EPT1,
  • KIAA1724,
  • SELI,
  • SEPI,
  • ethanolaminephosphotransferase 1,
  • SELI,
  • NM_033505.2,
  • uc021veu.2
  • identifiers:
  • 85465,
  • ENSG00000138018,

Genome feature

Region: gene ? Length: 49743  
Location: 2:26346143-26395885 Cyto location: 2p23.3

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0 Diseases

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736 SN Ps

5 Cross References

16 Data Sets

10 Homologues

0 Located Features

97 Rna Seq Results