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Gene : PPM1B Homo sapiens

Name  ? protein phosphatase, Mg2+/Mn2+ dependent 1B Cytological Location  2p21
Brief Description  protein phosphatase, Mg2 /Mn2 dependent 1B
Description  The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences. [provided by RefSeq, Jul 2008]
  • synonyms:
  • PP2CB,
  • protein phosphatase 2C, beta isoform,
  • NM_002706,
  • AJ005801,
  • OTTHUMG00000128757,
  • protein phosphatase 1B (formerly 2C), magnesium-dependent, beta isoform,
  • PP2C-beta,
  • PP2CB,
  • PP2C-beta-X,
  • HGNC:9276,
  • uc002rtt.4,
  • PPM1B,
  • protein phosphatase, Mg2+/Mn2+ dependent, 1B
  • identifiers:
  • 5495,
  • ENSG00000138032,
  • PPM1B

Genome feature

Region: gene ? Length: 78528  
Location: 2:44168803-44247330 Cyto location: 2p21

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0 Diseases

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502 SN Ps

5 Cross References

17 Data Sets

10 Homologues

0 Located Features

97 Rna Seq Results