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Gene : COX17 Homo sapiens

Name  ? cytochrome c oxidase copper chaperone COX17 Cytological Location  3q13.33
Brief Description  cytochrome c oxidase copper chaperone COX17
description  Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be involved in the recruitment of copper to mitochondria for incorporation into the COX apoenzyme. This protein shares 92% amino acid sequence identity with mouse and rat Cox17 proteins. This gene is no longer considered to be a candidate gene for COX deficiency. A pseudogene COX17P has been found on chromosome 13. [provided by RefSeq, Jul 2008]
  • synonyms:
  • uc003ecz.2,
  • COX17 (yeast) homolog, cytochrome c oxidase assembly protein,
  • OTTHUMG00000159433,
  • NM_005694,
  • COX17,
  • HGNC:2264,
  • COX17, cytochrome c oxidase copper chaperone,
  • L77701,
  • COX17 cytochrome c oxidase assembly homolog (S. cerevisiae)
  • identifiers:
  • 10063,
  • ENSG00000138495,
  • COX17

Genome feature

Region: gene ? Length: 7872  
Location: 3:119669525-119677396 reverse strand Cyto location: 3q13.33

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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Mouse Gene --> Allele [Phenotype]


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3756 SN Ps

5 Cross References

15 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results