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Gene : WARS1 Homo sapiens

Name  ? tryptophanyl-tRNA synthetase 1 Cytological Location  14q32.2
Brief Description  tryptophanyl-tRNA synthetase 1
Description  Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. Tryptophanyl-tRNA synthetase (WARS) catalyzes the aminoacylation of tRNA(trp) with tryptophan and is induced by interferon. Tryptophanyl-tRNA synthetase belongs to the class I tRNA synthetase family. Four transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • synonyms:
  • M61715,
  • IFI53,
  • WARS,
  • IFI53,
  • GAMMA-2,
  • tryptophanyl-tRNA synthetase,
  • WARS1,
  • OTTHUMG00000171572,
  • IFP53,
  • HMN9,
  • IFP53,
  • tryptophan tRNA ligase 1, cytoplasmic,
  • uc001yhl.2,
  • NM_004184,
  • WARS,
  • HGNC:12729
  • identifiers:
  • 7453,
  • ENSG00000140105,
  • WARS1

Genome feature

Region: gene ? Length: 42539  
Location: 14:100333789-100376327 reverse strand Cyto location: 14q32.2


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Disease

1 Diseases

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3756 SN Ps

5 Cross References

19 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results