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Gene : IQGAP1 Homo sapiens

Name  ? IQ motif containing GTPase activating protein 1 Cytological Location  15q26.1
Brief Description  IQ motif containing GTPase activating protein 1
description  This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines. [provided by RefSeq, Jul 2008]
  • synonyms:
  • KIAA0051,
  • NM_003870,
  • SAR1,
  • p195,
  • RasGAP-like with IQ motifs,
  • HUMORFA01,
  • IQGAP1,
  • HGNC:6110,
  • uc002bpl.2,
  • SAR1,
  • D29640,
  • p195,
  • OTTHUMG00000149832,
  • identifiers:
  • 8826,
  • ENSG00000140575,
  • IQGAP1

Genome feature

Region: gene ? Length: 113998  
Location: 15:90388242-90502239 Cyto location: 15q26.1

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



3756 SN Ps

5 Cross References

18 Data Sets

7 Homologues

3 Located Features

97 Rna Seq Results