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Gene : SCYL1 Homo sapiens

Name  ? SCY1 like pseudokinase 1 Cytological Location  11q13.1
Brief Description  SCY1 like pseudokinase 1
Description  This gene encodes a transcriptional regulator belonging to the SCY1-like family of kinase-like proteins. The protein has a divergent N-terminal kinase domain that is thought to be catalytically inactive, and can bind specific DNA sequences through its C-terminal domain. It activates transcription of the telomerase reverse transcriptase and DNA polymerase beta genes. The protein has been localized to the nucleus, and also to the cytoplasm and centrosomes during mitosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • synonyms:
  • SCY1-like 1 (S. cerevisiae),
  • uc001oea.2,
  • HT019,
  • TRAP,
  • SCAR21,
  • TEIF,
  • NTKL,
  • TEIF,
  • GKLP,
  • N-terminal kinase-like,
  • P105,
  • GKLP,
  • teratoma-associated tyrosine kinase,
  • MGC78454,
  • TRAP,
  • HT019,
  • HGNC:14372,
  • NKTL,
  • telomerase regulation-associated protein,
  • NTKL,
  • TAPK,
  • TAPK,
  • P105,
  • AF225424,
  • NM_020680,
  • NKTL,
  • SCY1-like, kinase-like 1,
  • OTTHUMG00000166325,
  • telomerase transcriptional elements-interacting factor,
  • SCYL1
  • identifiers:
  • 57410,
  • ENSG00000142186,
  • SCYL1

Genome feature

Region: gene ? Length: 13630  
Location: 11:65525081-65538710 Cyto location: 11q13.1


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Function

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

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Expression

Gene(s) --> Significant SNPs (GTex data)

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0 Pathways

162 SN Ps

5 Cross References

18 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results