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Gene : CEP170 Homo sapiens

Name  ? centrosomal protein 170 Cytological Location  1q43
Brief Description  centrosomal protein 170
Description  The product of this gene is a component of the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. During interphase, the encoded protein localizes to the sub-distal appendages of mature centrioles, which are microtubule-based structures thought to help organize centrosomes. During mitosis, the protein associates with spindle microtubules near the centrosomes. The protein interacts with and is phosphorylated by polo-like kinase 1, and functions in maintaining microtubule organization and cell morphology. The human genome contains a putative transcribed pseudogene. Several alternatively spliced transcript variants of this gene have been found, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]
  • synonyms:
  • FAM68A,
  • KARP 1 binding protein,
  • KAB,
  • AB022657,
  • CEP170,
  • KIAA0470,
  • XRCC5 binding protein,
  • OTTHUMG00000039862,
  • HGNC:28920,
  • NM_014812,
  • KIAA0470,
  • KAB,
  • centrosomal protein 170kDa,
  • uc057qug.1,
  • FAM68A
  • identifiers:
  • 9859,
  • ENSG00000143702,
  • CEP170

Genome feature

Region: gene ? Length: 131369  
Location: 1:243124428-243255796 reverse strand Cyto location: 1q43


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Function

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

0 Pathways

3753 SN Ps

5 Cross References

15 Data Sets

3 Homologues

0 Located Features

97 Rna Seq Results