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Gene : RPL7 Homo sapiens

Name  ? ribosomal protein L7 Cytological Location  8q21.11
Brief Description  ribosomal protein L7
Description  Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L30P family of ribosomal proteins. It contains an N-terminal basic region-leucine zipper (BZIP)-like domain and the RNP consensus submotif RNP2. In vitro the BZIP-like domain mediates homodimerization and stable binding to DNA and RNA, with a preference for 28S rRNA and mRNA. The protein can inhibit cell-free translation of mRNAs, suggesting that it plays a regulatory role in the translation apparatus. It is located in the cytoplasm. The protein has been shown to be an autoantigen in patients with systemic autoimmune diseases, such as systemic lupus erythematosus. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
  • synonyms:
  • HGNC:10363,
  • L16557,
  • humL7-1,
  • NM_000971,
  • uc064nrp.1,
  • OTTHUMG00000134312,
  • RPL7,
  • L7,
  • L7,
  • humL7-1
  • identifiers:
  • 6129,
  • ENSG00000147604,
  • RPL7

Genome feature

Region: gene ? Length: 4225  
Location: 8:73290242-73294466 reverse strand Cyto location: 8q21.11


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Genomics

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Proteins

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SNPs

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Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Expression

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Other

107 SN Ps

5 Cross References

15 Data Sets

10 Homologues

0 Located Features

97 Rna Seq Results