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Gene : EI24 Homo sapiens

Name  ? EI24 autophagy associated transmembrane protein Cytological Location  11q24.2
Brief Description  EI24 autophagy associated transmembrane protein
Description  This gene encodes a putative tumor suppressor and has higher expression in p53-expressing cells than in control cells and is an immediate-early induction target of p53-mediated apoptosis. The encoded protein may suppress cell growth by inducing apoptotic cell death through the caspase 9 and mitochondrial pathways. This gene is located on human chromosome 11q24, a region frequently altered in cancers. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 1, 3, 7, and 8. [provided by RefSeq, Feb 2014]
  • synonyms:
  • PIG8,
  • NM_004879,
  • AF010313,
  • EI24,
  • TP53I8,
  • PIG8,
  • etoposide induced 2.4,
  • EPG4,
  • ectopic P-granules autophagy protein 4 homolog (C. elegans),
  • uc031yiu.2,
  • TP53I8,
  • etoposide induced 2.4 mRNA,
  • EPG4,
  • OTTHUMG00000165851,
  • HGNC:13276
  • identifiers:
  • 9538,
  • ENSG00000149547,
  • EI24

Genome feature

Region: gene ? Length: 15469  
Location: 11:125569216-125584684 Cyto location: 11q24.2

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1 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



1 Pathways

3753 SN Ps

5 Cross References

16 Data Sets

5 Homologues

0 Located Features

97 Rna Seq Results