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Gene : DSPP Homo sapiens

Name  ? dentin sialophosphoprotein Cytological Location  4q22.1
Brief Description  dentin sialophosphoprotein
Description  This gene encodes a member of the small integrin-binding ligand N-linked glycoprotein (SIBLING) family of proteins. The encoded preproprotein is secreted by odontoblasts and proteolytically processed to generate two principal proteins of the dentin extracellular matrix of the tooth, dentin sialoprotein and dentin phosphoprotein. These two protein products may play distinct but related roles in dentin mineralization. Mutations in this gene are associated with dentinogenesis imperfecta and dentin dysplasia. This gene is present in a gene cluster on chromosome 4. Allelic differences due to repeat polymorphisms have been found for this gene. [provided by RefSeq, Jan 2016]
  • synonyms:
  • DSP,
  • DMP3,
  • DGI1,
  • DPP,
  • OTTHUMG00000161061,
  • DSPP,
  • DMP3,
  • AF163151,
  • DFNA39,
  • DFNA39,
  • DGI1,
  • NM_014208,
  • uc003hqu.3,
  • HGNC:3054
  • identifiers:
  • 1834,
  • ENSG00000152591,
  • DSPP

Genome feature

Region: gene ? Length: 8345  
Location: 4:87608529-87616873 Cyto location: 4q22.1


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Function

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Proteins

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SNPs

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Disease

4 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

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Other

0 SN Ps

5 Cross References

15 Data Sets

2 Homologues

0 Located Features

97 Rna Seq Results