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Gene : MR1 Homo sapiens

Name  ? major histocompatibility complex, class I-related Cytological Location  1q25.3
Brief Description  major histocompatibility complex, class I-related
Description  MAIT (mucosal-associated invariant T-cells) lymphocytes represent a small population of T-cells primarily found in the gut. The protein encoded by this gene is an antigen-presenting molecule that presents metabolites of microbial vitamin B to MAITs. This presentation may activate the MAITs to regulate the amounts of specific types of bacteria in the gut. Several transcript variants encoding different isoforms have been found for this gene, and a pseudogene of it has been detected about 36 kbp upstream on the same chromosome. [provided by RefSeq, Jul 2015]
  • synonyms:
  • uc001goq.2,
  • MR1,
  • HGNC:4975,
  • HLALS,
  • OTTHUMG00000035175,
  • AF010446,
  • NM_001531,
  • major histocompatibility complex, class I-like sequence,
  • HLALS
  • identifiers:
  • 3140,
  • ENSG00000153029,
  • MR1

Genome feature

Region: gene ? Length: 28547  
Location: 1:181033392-181061938 Cyto location: 1q25.3


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Function

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Gene --> Orthologues

Interactions

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Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

0 Pathways

856 SN Ps

5 Cross References

17 Data Sets

47 Homologues

0 Located Features

97 Rna Seq Results