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Gene : ZFYVE27 Homo sapiens

Name  ? zinc finger FYVE-type containing 27 Cytological Location  10q24.2
Brief Description  zinc finger FYVE-type containing 27
Description  This gene encodes a protein with several transmembrane domains, a Rab11-binding domain and a lipid-binding FYVE finger domain. The encoded protein appears to promote neurite formation. A mutation in this gene has been reported to be associated with hereditary spastic paraplegia, however the pathogenicity of the mutation, which may simply represent a polymorphism, is unclear. [provided by RefSeq, Mar 2010]
  • synonyms:
  • protrudin,
  • ZFYVE27,
  • SPG33,
  • uc001kom.3,
  • zinc finger, FYVE domain containing 27,
  • HGNC:26559,
  • SPG33,
  • BC030621,
  • NM_144588,
  • OTTHUMG00000018867,
  • FLJ32919
  • identifiers:
  • 118813,
  • ENSG00000155256,
  • ZFYVE27

Genome feature

Region: gene ? Length: 23787  
Location: 10:97737121-97760907 Cyto location: 10q24.2

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



0 Pathways

3753 SN Ps

5 Cross References

17 Data Sets

3 Homologues

0 Located Features

97 Rna Seq Results