help  | about  | cite  | software

Gene : CUL4B Homo sapiens

Name  ? cullin 4B Cytological Location  Xq24
Brief Description  cullin 4B
Description  This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • synonyms:
  • CUL-4B,
  • OTTHUMG00000022302,
  • HGNC:2555,
  • MRXSC,
  • CUL4B,
  • MRXS15,
  • U58091,
  • uc004esw.4,
  • SFM2,
  • MRXHF2,
  • NM_003588
  • identifiers:
  • 8450,
  • ENSG00000158290,
  • CUL4B

Genome feature

Region: gene ? Length: 51241  
Location: X:120524589-120575829 reverse strand Cyto location: Xq24


Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer

Function

Gene Ontology Displayer

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

Homologue Displayer

Gene --> Orthologues

Interactions

Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

495 SN Ps

5 Cross References

19 Data Sets

11 Homologues

0 Located Features

97 Rna Seq Results