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Gene : MST1R Homo sapiens

Name  ? macrophage stimulating 1 receptor Cytological Location  3p21.31
Brief Description  macrophage stimulating 1 receptor
description  This gene encodes a cell surface receptor for macrophage-stimulating protein (MSP) with tyrosine kinase activity. The mature form of this protein is a heterodimer of disulfide-linked alpha and beta subunits, generated by proteolytic cleavage of a single-chain precursor. The beta subunit undergoes tyrosine phosphorylation upon stimulation by MSP. This protein is expressed on the ciliated epithelia of the mucociliary transport apparatus of the lung, and together with MSP, thought to be involved in host defense. Alternative splicing generates multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Jan 2016]
  • synonyms:
  • CD136,
  • PTK8,
  • NPCA3,
  • OTTHUMG00000156709,
  • PTK8,
  • uc003cxy.5,
  • HGNC:7381,
  • PTK8 protein tyrosine kinase 8,
  • SEA,
  • MST1R,
  • CDw136,
  • S13 erythroblastosis (avian) oncogene homolog,
  • X70040,
  • c-met-related tyrosine kinase,
  • SEA,
  • NM_001244937,
  • RON,
  • RON,
  • CDw136,
  • CD136,
  • S13 avian erythroblastosis oncogene homolog
  • identifiers:
  • 4486,
  • ENSG00000164078,
  • MST1R

Genome feature

Region: gene ? Length: 17403  
Location: 3:49886471-49903873 reverse strand Cyto location: 3p21.31


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Disease

1 Diseases

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3756 SN Ps

5 Cross References

19 Data Sets

59 Homologues

0 Located Features

97 Rna Seq Results