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Gene : F2RL1 Homo sapiens

Name  ? F2R like trypsin receptor 1 Cytological Location  5q13.3
Brief Description  F2R like trypsin receptor 1
Description  This gene encodes a member of the G-protein coupled receptor 1 family of proteins. The encoded cell surface receptor is activated through proteolytic cleavage of its extracellular amino terminus, resulting in a new amino terminus that acts as a tethered ligand that binds to an extracellular loop domain. Activation of the receptor has been shown to stimulate vascular smooth muscle relaxation, dilate blood vessels, increase blood flow, and lower blood pressure. This protein is also important in the inflammatory response, as well as innate and adaptive immunity. [provided by RefSeq, Jun 2016]
  • synonyms:
  • proteinase-activated receptor-2,
  • F2RL1,
  • coagulation factor II (thrombin) receptor-like 1,
  • PAR2,
  • GPR11,
  • NM_005242,
  • PAR2,
  • uc003keo.4,
  • OTTHUMG00000102118,
  • GPR11,
  • BC018130,
  • HGNC:3538
  • identifiers:
  • 2150,
  • ENSG00000164251,
  • F2RL1

Genome feature

Region: gene ? Length: 16286  
Location: 5:76819030-76835315 Cyto location: 5q13.3


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Disease

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3756 SN Ps

5 Cross References

17 Data Sets

20 Homologues

0 Located Features

97 Rna Seq Results