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Gene : INPPL1 Homo sapiens

Name  ? inositol polyphosphate phosphatase like 1 Cytological Location  11q13.4
Brief Description  inositol polyphosphate phosphatase like 1
Description  The protein encoded by this gene is an SH2-containing 5'-inositol phosphatase that is involved in the regulation of insulin function. The encoded protein also plays a role in the regulation of epidermal growth factor receptor turnover and actin remodelling. Additionally, this gene supports metastatic growth in breast cancer and is a valuable biomarker for breast cancer. [provided by RefSeq, Jan 2009]
  • synonyms:
  • OTTHUMG00000167879,
  • SHIP2,
  • HGNC:6080,
  • SHIP2,
  • 51C protein,
  • SH2 domain-containing inositol 5'-phosphatase 2,
  • INPPL1,
  • NM_001567,
  • Y14385,
  • uc001osf.4,
  • phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2,
  • OPSMD
  • identifiers:
  • 3636,
  • ENSG00000165458,
  • INPPL1

Genome feature

Region: gene ? Length: 15287  
Location: 11:72223861-72239147 Cyto location: 11q13.4


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Function

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Gene --> Orthologues

Interactions

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Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

432 SN Ps

5 Cross References

19 Data Sets

7 Homologues

0 Located Features

97 Rna Seq Results