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Gene : ARHGAP42 Homo sapiens

Name  ? Rho GTPase activating protein 42 Cytological Location  11q22.1
Brief Description  Rho GTPase activating protein 42
Description  This gene encodes a Rho GTPase-activating protein (RhoGAP), and member of the GRAF or BAR-PH family of proteins. Expression of this gene is enriched in vascular smooth muscle cells and the encoded protein inhibits RhoA activity to regulate vascular tone and control blood pressure. A mutation in the first intron of this gene modulates its expression and is associated with reduced blood pressure in human patients with borderline hypertension. [provided by RefSeq, Jul 2017]
  • synonyms:
  • HGNC:26545,
  • uc001pge.2,
  • TMEM133,
  • ARHGAP42,
  • OTTHUMG00000167530,
  • AD031,
  • AD031,
  • GRAF3,
  • transmembrane protein 133,
  • FLJ32810,
  • GRAF3,
  • NM_152432,
  • TMEM133
  • identifiers:
  • 143872,
  • ENSG00000165895,
  • ARHGAP42

Genome feature

Region: gene ? Length: 306654  
Location: 11:100687288-100993941 Cyto location: 11q22.1

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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene(s) --> Significant SNPs (GTex data)

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3753 SN Ps

5 Cross References

16 Data Sets

5 Homologues

0 Located Features

97 Rna Seq Results