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Gene : PRKCB Homo sapiens

Name  ? protein kinase C beta Cytological Location  16p12.2-p12.1
Brief Description  protein kinase C beta
Description  Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
  • synonyms:
  • PRKCB2,
  • PKCB,
  • PKCB,
  • PRKCB,
  • HGNC:9395,
  • PKCĪ²,
  • NM_212535,
  • PRKCB1,
  • PRKCB1,
  • M13975,
  • PKCI(2),
  • uc002dmd.4,
  • protein kinase C, beta 1,
  • OTTHUMG00000131615,
  • PKCbeta,
  • PRKCB2,
  • protein kinase C, beta,
  • PKC-beta
  • identifiers:
  • 5579,
  • ENSG00000166501,
  • PRKCB

Genome feature

Region: gene ? Length: 384629  
Location: 16:23835983-24220611 Cyto location: 16p12.2-p12.1


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74 Pathways

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0 Diseases

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74 Pathways

3756 SN Ps

5 Cross References

18 Data Sets

40 Homologues

0 Located Features

97 Rna Seq Results