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Gene : B2M Homo sapiens

Name  ? beta-2-microglobulin Cytological Location  15q21.1
Brief Description  beta-2-microglobulin
Description  This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.[provided by RefSeq, Aug 2014]
  • synonyms:
  • AB021288,
  • OTTHUMG00000131247,
  • IMD43,
  • uc001zuc.4,
  • B2M,
  • NM_004048,
  • HGNC:914
  • identifiers:
  • 567,
  • ENSG00000166710,
  • B2M

Genome feature

Region: gene ? Length: 7386  
Location: 15:44711492-44718877 Cyto location: 15q21.1


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Function

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

2 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Gene --> Orthologues

Interactions

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Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

63 SN Ps

5 Cross References

19 Data Sets

20 Homologues

0 Located Features

97 Rna Seq Results