help  | about  | cite  | software

Gene : TMED10 Homo sapiens

Name  ? transmembrane p24 trafficking protein 10 Cytological Location  14q24.3
Brief Description  transmembrane p24 trafficking protein 10
description  This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8. [provided by RefSeq, Jul 2008]
  • synonyms:
  • Tmp-21-I,
  • TMP21,
  • p24delta1,
  • HGNC:16998,
  • OTTHUMG00000171771,
  • uc001xrm.2,
  • S31I125,
  • TMP21,
  • P24(DELTA),
  • NM_006827,
  • p24d1,
  • TMED10,
  • p24d1,
  • P24(DELTA),
  • p23,
  • p23,
  • AL832012,
  • X97442,
  • transmembrane emp24-like trafficking protein 10 (yeast),
  • S31III125
  • identifiers:
  • 10972,
  • ENSG00000170348,
  • TMED10

Genome feature

Region: gene ? Length: 45144  
Location: 14:75131469-75176612 reverse strand Cyto location: 14q24.3

Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer


Gene Ontology Displayer

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


Homologue Displayer

Gene --> Orthologues


Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



652 SN Ps

5 Cross References

16 Data Sets

16 Homologues

0 Located Features

97 Rna Seq Results