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Gene : SOSTDC1 Homo sapiens

Name  ? sclerostin domain containing 1 Cytological Location  7p21.2
Brief Description  sclerostin domain containing 1
Description  This gene is a member of the sclerostin family and encodes an N-glycosylated, secreted protein with a C-terminal cystine knot-like domain. This protein functions as a bone morphogenetic protein (BMP) antagonist. Specifically, it directly associates with BMPs, prohibiting them from binding their receptors, thereby regulating BMP signaling during cellular proliferation, differentiation, and programmed cell death. [provided by RefSeq, Jul 2008]
  • synonyms:
  • AB059270,
  • uc003stg.4,
  • HGNC:21748,
  • ectodin,
  • OTTHUMG00000090807,
  • wise,
  • USAG1,
  • DAND7,
  • USAG1,
  • CDA019,
  • DKFZp564D206,
  • DAND7,
  • SOSTDC1,
  • NM_015464
  • identifiers:
  • 25928,
  • ENSG00000171243,

Genome feature

Region: gene ? Length: 4258  
Location: 7:16461481-16465738 reverse strand Cyto location: 7p21.2

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



0 Pathways

3753 SN Ps

5 Cross References

14 Data Sets

4 Homologues

0 Located Features

97 Rna Seq Results