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Gene : GLRX Homo sapiens

Name  ? glutaredoxin Cytological Location  5q15
Brief Description  glutaredoxin
Description  This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Aug 2011]
  • synonyms:
  • HGNC:4330,
  • NM_002064,
  • GRX1,
  • GRX,
  • thioltransferase,
  • GRX,
  • OTTHUMG00000121167,
  • uc063fnd.1,
  • glutaredoxin (thioltransferase),
  • GRX1,
  • GLRX
  • identifiers:
  • 2745,
  • ENSG00000173221,
  • GLRX

Genome feature

Region: gene ? Length: 9025  
Location: 5:95813849-95822873 reverse strand Cyto location: 5q15


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Proteins

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SNPs

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Disease

0 Diseases

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Expression

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Other

531 SN Ps

5 Cross References

15 Data Sets

8 Homologues

0 Located Features

97 Rna Seq Results