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Gene : OLR1 Homo sapiens

Name  ? oxidized low density lipoprotein receptor 1 Cytological Location  12p13.2
Brief Description  oxidized low density lipoprotein receptor 1
description  This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]
  • synonyms:
  • OTTHUMG00000168527,
  • uc001qxo.2,
  • D89050,
  • CLEC8A,
  • NM_002543,
  • oxidised low density lipoprotein (lectin-like) receptor 1,
  • LOX1,
  • CLEC8A,
  • HGNC:8133,
  • LOX-1,
  • SCARE1,
  • SLOX1,
  • SCARE1,
  • OLR1,
  • identifiers:
  • 4973,
  • ENSG00000173391,
  • OLR1

Genome feature

Region: gene ? Length: 13892  
Location: 12:10158300-10172191 reverse strand Cyto location: 12p13.2

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1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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483 SN Ps

5 Cross References

17 Data Sets

2 Homologues

0 Located Features

97 Rna Seq Results