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Gene : H1-8 Homo sapiens

Name  ? H1.8 linker histone Cytological Location  3q22.1
Brief Description  H1.8 linker histone
Description  Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. The protein encoded is a replication-independent histone that is a member of the histone H1 family. This gene contains introns, unlike most histone genes. The related mouse gene is expressed only in oocytes. [provided by RefSeq, Oct 2015]
  • synonyms:
  • H1oo,
  • H1 histone family, member O, oocyte-specific,
  • H1 histone family member O oocyte specific,
  • AY158091,
  • HGNC:18463,
  • H1.8,
  • H1-8,
  • osH1,
  • NM_153833,
  • OTTHUMG00000159541,
  • H1FOO,
  • H1FOO,
  • uc003emu.3
  • identifiers:
  • 132243,
  • ENSG00000178804,
  • H1-8

Genome feature

Region: gene ? Length: 11972  
Location: 3:129543214-129555185 Cyto location: 3q22.1


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Function

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Gene --> Orthologues

Interactions

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Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

0 Pathways

313 SN Ps

3 Cross References

14 Data Sets

15 Homologues

0 Located Features

97 Rna Seq Results