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Gene : PER1 Homo sapiens

Name  ? period circadian regulator 1 Cytological Location  17p13.1
Brief Description  period circadian regulator 1
Description  This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene may increase the risk of getting certain cancers. Alternative splicing has been observed in this gene; however, these variants have not been fully described. [provided by RefSeq, Jan 2014]
  • synonyms:
  • PER,
  • HGNC:8845,
  • RIGUI,
  • PER1,
  • period homolog 1 (Drosophila),
  • OTTHUMG00000178317,
  • period (Drosophila) homolog 1,
  • NM_002616,
  • hPER,
  • period circadian clock 1,
  • AB002107,
  • PER,
  • uc002gkd.4,
  • RIGUI
  • identifiers:
  • 5187,
  • ENSG00000179094,
  • PER1

Genome feature

Region: gene ? Length: 15891  
Location: 17:8140470-8156360 reverse strand Cyto location: 17p13.1


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Disease

0 Diseases

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Other

2 SN Ps

5 Cross References

15 Data Sets

8 Homologues

0 Located Features

97 Rna Seq Results