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Gene : LACC1 Homo sapiens

Name  ? laccase domain containing 1 Cytological Location  13q14.11
Brief Description  laccase domain containing 1
Description  This gene encodes an oxidoreductase that promotes fatty-acid oxidation, with concomitant inflammasome activation, mitochondrial and NADPH-oxidase-dependent reactive oxygen species production, and bactericidal activity of macrophages. The encoded protein forms a complex with fatty acid synthase on peroxisomes and is thought to be modulated by peroxisome proliferator-activated receptor signaling events. Naturally occurring mutations in this gene are associated with inflammatory bowel disease, Behcet's disease, leprosy, ulcerative colitis, early-onset Crohn's disease, and systemic juvenile idiopathic arthritis. [provided by RefSeq, Apr 2017]
  • synonyms:
  • laccase (multicopper oxidoreductase) domain containing 1,
  • C13orf31,
  • FAMIN,
  • fatty acid metabolism–immunity nexus,
  • AK096044,
  • OTTHUMG00000016826,
  • C13orf31,
  • NM_153218,
  • HGNC:26789,
  • JUVAR,
  • FAMIN,
  • chromosome 13 open reading frame 31,
  • LACC1,
  • FLJ38725,
  • uc010acg.4
  • identifiers:
  • 144811,
  • ENSG00000179630,
  • LACC1

Genome feature

Region: gene ? Length: 14755  
Location: 13:43879178-43893932 Cyto location: 13q14.11

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



0 Pathways

3753 SN Ps

5 Cross References

17 Data Sets

3 Homologues

0 Located Features

97 Rna Seq Results