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Gene : SHMT2 Homo sapiens

Name  ? serine hydroxymethyltransferase 2 Cytological Location  12q13.3
Brief Description  serine hydroxymethyltransferase 2
Description  This gene encodes the mitochondrial form of a pyridoxal phosphate-dependent enzyme that catalyzes the reversible reaction of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. The encoded product is primarily responsible for glycine synthesis. The activity of the encoded protein has been suggested to be the primary source of intracellular glycine. The gene which encodes the cytosolic form of this enzyme is located on chromosome 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
  • synonyms:
  • SHMT2,
  • SHMT,
  • AK223555,
  • uc001snf.3,
  • OTTHUMG00000171246,
  • NM_005412,
  • serine hydroxymethyltransferase 2 (mitochondrial),
  • HEL-S-51e,
  • SHMT,
  • HGNC:10852,
  • GLYA
  • identifiers:
  • 6472,
  • ENSG00000182199,
  • SHMT2

Genome feature

Region: gene ? Length: 5251  
Location: 12:57229685-57234935 Cyto location: 12q13.3


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Genomics

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Proteins

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SNPs

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Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Expression

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Other

54 SN Ps

5 Cross References

16 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results