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Gene : RGS6 Homo sapiens

Name  ? regulator of G protein signaling 6 Cytological Location  14q24.2
Brief Description  regulator of G protein signaling 6
Description  This gene encodes a member of the RGS (regulator of G protein signaling) family of proteins, which are defined by the presence of a RGS domain that confers the GTPase-activating activity of these proteins toward certain G alpha subunits. This protein also belongs to a subfamily of RGS proteins characterized by the presence of DEP and GGL domains, the latter a G beta 5-interacting domain. The RGS proteins negatively regulate G protein signaling, and may modulate neuronal, cardiovascular, lymphocytic activities, and cancer risk. Many alternatively spliced transcript variants encoding different isoforms with long or short N-terminal domains, complete or incomplete GGL domains, and distinct C-terminal domains, have been described for this gene, however, the full-length nature of some of these variants is not known.[provided by RefSeq, Mar 2011]
  • synonyms:
  • GAP,
  • OTTHUMG00000171340,
  • AF073920,
  • HGNC:10002,
  • NM_001204416,
  • regulator of G-protein signaling 6,
  • uc001xmx.5,
  • RGS6,
  • HA117,
  • regulator of G-protein signalling 6,
  • S914
  • identifiers:
  • 9628,
  • ENSG00000182732,
  • RGS6

Genome feature

Region: gene ? Length: 765082  
Location: 14:71867397-72632478 Cyto location: 14q24.2


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Disease

0 Diseases

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3756 SN Ps

5 Cross References

17 Data Sets

8 Homologues

0 Located Features

97 Rna Seq Results