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Gene : KREMEN1 Homo sapiens

Name  ? kringle containing transmembrane protein 1 Cytological Location  22q12.1
Brief Description  kringle containing transmembrane protein 1
Description  This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Jul 2008]
  • synonyms:
  • OTTHUMG00000030987,
  • KREMEN,
  • AB059618,
  • kringle containing transmembrane protein,
  • NM_001039570,
  • ECTD13,
  • HGNC:17550,
  • uc011akm.2,
  • KREMEN,
  • KREMEN1,
  • KRM1,
  • KRM1
  • identifiers:
  • 83999,
  • ENSG00000183762,
  • KREMEN1

Genome feature

Region: gene ? Length: 95299  
Location: 22:29073035-29168333 Cyto location: 22q12.1


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Proteins

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SNPs

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Disease

1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Gene -> HPO annotation (Human Phenotype Ontology)

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Expression

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Other

3756 SN Ps

4 Cross References

15 Data Sets

4 Homologues

0 Located Features

97 Rna Seq Results