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Gene : GABRD Homo sapiens

Name  ? gamma-aminobutyric acid type A receptor delta subunit Cytological Location  1p36.33
Brief Description  gamma-aminobutyric acid type A receptor delta subunit
Description  Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho. This gene encodes the delta subunit. Mutations in this gene have been associated with susceptibility to generalized epilepsy with febrile seizures, type 5. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
  • synonyms:
  • NM_000815,
  • OTTHUMG00000041064,
  • GEFSP5,
  • BC033801,
  • GABRD,
  • GABA(A) receptor, delta,
  • EIG10,
  • gamma-aminobutyric acid (GABA) A receptor, delta,
  • uc001aip.3,
  • HGNC:4084,
  • EJM7
  • identifiers:
  • 2563,
  • ENSG00000187730,
  • GABRD

Genome feature

Region: gene ? Length: 11414  
Location: 1:2019345-2030758 Cyto location: 1p36.33


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Disease

1 Diseases

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137 SN Ps

5 Cross References

19 Data Sets

55 Homologues

0 Located Features

97 Rna Seq Results