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Gene : EPHB4 Homo sapiens

Name  ? EPH receptor B4 Cytological Location  7q22.1
Brief Description  EPH receptor B4
Description  Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development. [provided by RefSeq, Jul 2008]
  • synonyms:
  • CMAVM2,
  • HTK,
  • OTTHUMG00000157040,
  • EphB4,
  • HFASD,
  • EPHB4,
  • TYRO11,
  • NM_004444,
  • MYK1,
  • HTK,
  • LMPHM7,
  • uc003uwn.2,
  • Tyro11,
  • HGNC:3395,
  • AY056047
  • identifiers:
  • 2050,
  • ENSG00000196411,
  • EPHB4

Genome feature

Region: gene ? Length: 24959  
Location: 7:100802565-100827523 reverse strand Cyto location: 7q22.1


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Function

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Gene -> HPO annotation (Human Phenotype Ontology)

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Genomics

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Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

2 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

3756 SN Ps

5 Cross References

20 Data Sets

59 Homologues

0 Located Features

97 Rna Seq Results