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Gene : MRTFA Homo sapiens

Name  ? myocardin related transcription factor A Cytological Location  22q13.1-q13.2
Brief Description  myocardin related transcription factor A
Description  The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
  • synonyms:
  • BSAC,
  • MRTF-A,
  • megakaryocytic acute leukemia,
  • MKL1,
  • MAL,
  • MRTF-A,
  • MRTFA,
  • megakaryoblastic leukemia (translocation) 1,
  • HGNC:14334,
  • MKL,
  • NM_020831,
  • BSAC,
  • KIAA1438,
  • MAL,
  • MKL1,
  • OTTHUMG00000151146,
  • AB037859,
  • basic, SAP and coiled-coil domain,
  • uc032qph.2,
  • MKL
  • identifiers:
  • 57591,
  • ENSG00000196588,

Genome feature

Region: gene ? Length: 226431  
Location: 22:40410289-40636719 reverse strand Cyto location: 22q13.1-q13.2

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1 Diseases

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3753 SN Ps

5 Cross References

18 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results