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Gene : SIPA1 Homo sapiens

Name  ? signal-induced proliferation-associated 1 Cytological Location  11q13.1
Brief Description  signal-induced proliferation-associated 1
Description  The product of this gene is a mitogen induced GTPase activating protein (GAP). It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. This protein may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. It is localized to the perinuclear region. Two alternatively spliced variants encoding the same isoform have been characterized to date. [provided by RefSeq, Jul 2008]
  • synonyms:
  • AH006363,
  • BC010492,
  • SPA1,
  • BM677738,
  • NM_006747,
  • OTTHUMG00000166541,
  • uc058dmg.1,
  • SIPA1,
  • SPA1,
  • HGNC:10885
  • identifiers:
  • 6494,
  • ENSG00000213445,
  • SIPA1

Genome feature

Region: gene ? Length: 12830  
Location: 11:65638101-65650930 Cyto location: 11q13.1

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

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Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



3756 SN Ps

5 Cross References

17 Data Sets

9 Homologues

0 Located Features

97 Rna Seq Results