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Gene : RNF103 Homo sapiens

Name  ? ring finger protein 103 Cytological Location  2p11.2
Brief Description  ring finger protein 103
Description  The protein encoded by this gene contains a RING-H2 finger, a motif known to be involved in protein-protein and protein-DNA interactions. This gene is highly expressed in normal cerebellum, but not in the cerebral cortex. The expression of the rat counterpart in the frontal cortex and hippocampus was shown to be induced by elctroconvulsive treatment (ECT) as well as chronic antidepressant treatment, suggesting that this gene may be a molecular target for ECT and antidepressants. The protein is a ubiquitin ligase that functions in the endoplasmic reticulum-associated degradation pathway. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream CHMP3 (charged multivesicular body protein 3) gene. [provided by RefSeq, Oct 2011]
  • synonyms:
  • ZFP-103,
  • RNF103,
  • D76444,
  • HGNC:12859,
  • OTTHUMG00000153197,
  • hkf-1,
  • KF1,
  • NM_005667,
  • KF-1,
  • KF1,
  • ZFP103,
  • HKF-1,
  • zinc finger protein 103 homolog (mouse),
  • ZFP103,
  • uc002srn.4
  • identifiers:
  • 7844,
  • ENSG00000239305,
  • RNF103

Genome feature

Region: gene ? Length: 20485  
Location: 2:86603393-86623877 reverse strand Cyto location: 2p11.2


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Disease

0 Diseases

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Expression

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Other

816 SN Ps

5 Cross References

15 Data Sets

4 Homologues

0 Located Features

97 Rna Seq Results