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Gene : TAS2R38 Homo sapiens

Name  ? taste 2 receptor member 38 Cytological Location  7q34
Brief Description  taste 2 receptor member 38
description  This gene encodes a seven-transmembrane G protein-coupled receptor that controls the ability to taste glucosinolates, a family of bitter-tasting compounds found in plants of the Brassica sp. Synthetic compounds phenylthiocarbamide (PTC) and 6-n-propylthiouracil (PROP) have been identified as ligands for this receptor and have been used to test the genetic diversity of this gene. Although several allelic forms of this gene have been identified worldwide, there are two predominant common forms (taster and non-taster) found outside of Africa. These alleles differ at three nucleotide positions resulting in amino acid changes in the protein (A49P, A262V, and V296I) with the amino acid combination PAV identifying the taster variant (and AVI identifying the non-taster variant). [provided by RefSeq, Oct 2009]
  • synonyms:
  • T2R38,
  • PTC,
  • uc003vwx.1,
  • AF494231,
  • NM_176817,
  • HGNC:9584,
  • TAS2R38,
  • PTC,
  • OTTHUMG00000158374,
  • T2R61,
  • THIOT,
  • T2R61,
  • phenylthiocarbamide tasting,
  • taste receptor, type 2, member 38
  • identifiers:
  • 5726,
  • ENSG00000257138,
  • TAS2R38

Genome feature

Region: gene ? Length: 1143  
Location: 7:141972631-141973773 reverse strand Cyto location: 7q34

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1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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0 SN Ps

4 Cross References

13 Data Sets

31 Homologues

0 Located Features

97 Rna Seq Results