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Gene : SRD5A2 Homo sapiens

Name  ? steroid 5 alpha-reductase 2 Cytological Location  2p23.1
Brief Description  steroid 5 alpha-reductase 2
Description  This gene encodes a microsomal protein expressed at high levels in androgen-sensitive tissues such as the prostate. The encoded protein is active at acidic pH and is sensitive to the 4-azasteroid inhibitor finasteride. Deficiencies in this gene can result in male pseudohermaphroditism, specifically pseudovaginal perineoscrotal hypospadias (PPSH). [provided by RefSeq, Jul 2008]
  • synonyms:
  • SRD5A2,
  • NM_000348,
  • uc032nip.2,
  • steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2),
  • OTTHUMG00000152057,
  • HGNC:11285,
  • 3-oxo-5-alpha-steroid 4-dehydrogenase 2,
  • M74047
  • identifiers:
  • 6716,
  • ENSG00000277893,
  • SRD5A2

Genome feature

Region: gene ? Length: 143172  
Location: 2:31522480-31665651 reverse strand Cyto location: 2p23.1


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Function

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

763 SN Ps

4 Cross References

17 Data Sets

10 Homologues

0 Located Features

97 Rna Seq Results