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Gene : AKT3 Homo sapiens

Name  ? AKT serine/threonine kinase 3 Cytological Location  1q43-q44
Brief Description  AKT serine/threonine kinase 3
Description  The protein encoded by this gene is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. This kinase has been shown to be stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1). Alternatively splice transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
  • synonyms:
  • RAC-gamma,
  • AF124141,
  • RAC-gamma,
  • PRKBG,
  • NM_181690,
  • v-akt murine thymoma viral oncogene homolog 3,
  • protein kinase B, gamma,
  • AKT3,
  • RAC-PK-gamma,
  • STK-2,
  • MPPH2,
  • MPPH,
  • PRKBG,
  • PKBG,
  • PKBG,
  • OTTHUMG00000039994,
  • uc057qvr.1,
  • HGNC:393,
  • identifiers:
  • 10000,
  • ENSG00000117020,
  • AKT3

Genome feature

Region: gene ? Length: 362847  
Location: 1:243488233-243851079 reverse strand Cyto location: 1q43-q44

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67 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Chromosomal location.

Gene --> GO terms.

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Gene --> Proteins.


Gene Report --> GWAS hit


1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



67 Pathways

90 SNPs

5 Cross References

19 Data Sets

8 Homologues

0 Located Features

97 Rna Seq Results