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Gene : HOTAIR Homo sapiens

Name  ? HOX transcript antisense RNA Cytological Location  12q13.13
Brief Description  HOX transcript antisense RNA
Description  This gene is located within the Homeobox C (HOXC) gene cluster on chromosome 12 and is co-expressed with the HOXC genes. It functions through an RNA product, which binds lysine specific demethylase 1 (LSD1) and Polycomb repressive complex 2 (PRC2), and serves as a scaffold to assemble these regulators at the HOXD gene cluster, thereby promoting epigenetic repression of HOXD. This gene is highly expressed in multiple tumors. Alternatively spliced transcript variants have been identified. [provided by RefSeq, Feb 2019]
  • synonyms:
  • NR_003716,
  • NCRNA00072,
  • HGNC:33510,
  • NCRNA00072,
  • HOXC cluster antisense RNA 4 (non-protein coding),
  • HOXC11-AS1,
  • HOXC-AS4,
  • DQ926657,
  • HOTAIR,
  • HOXAS,
  • uc009zne.5,
  • HOX transcript antisense RNA (non-protein coding),
  • OTTHUMG00000152934,
  • non-protein coding RNA 72,
  • HOXC11-AS1,
  • HOXC-AS4
  • identifiers:
  • 100124700,
  • ENSG00000228630,
  • HOTAIR

Genome feature

Region: gene ? Length: 12649  
Location: 12:53962308-53974956 reverse strand Cyto location: 12q13.13


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Function

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

0 Pathways

409 SN Ps

5 Cross References

10 Data Sets

0 Homologues

0 Located Features

54 Rna Seq Results