help  | about  | cite  | software

Gene : HDAC6 Homo sapiens

Name  ? histone deacetylase 6 Cytological Location  Xp11.23
Brief Description  histone deacetylase 6
Description  Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription. [provided by RefSeq, Jul 2008]
  • synonyms:
  • CPBHM,
  • HDAC6,
  • HGNC:14064,
  • FLJ16239,
  • JM21,
  • AF132609,
  • HD6,
  • HD6,
  • uc004dks.2,
  • NM_006044,
  • OTTHUMG00000034496,
  • PPP1R90,
  • KIAA0901,
  • protein phosphatase 1, regulatory subunit 90,
  • PPP1R90,
  • JM21
  • identifiers:
  • 10013,
  • ENSG00000094631,
  • HDAC6

Genome feature

Region: gene ? Length: 23585  
Location: X:48801398-48824982 Cyto location: Xp11.23


Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer

Function

Gene Ontology Displayer

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

Homologue Displayer

Interactions

Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

4 SN Ps

5 Cross References

19 Data Sets

5 Homologues

0 Located Features

97 Rna Seq Results