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Gene : HDAC5 Homo sapiens

Name  ? histone deacetylase 5 Cytological Location  17q21.31
Brief Description  histone deacetylase 5
Description  Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • synonyms:
  • HGNC:14068,
  • NM_001015053,
  • HDAC5,
  • NY-CO-9,
  • AF249731,
  • NY-CO-9,
  • FLJ90614,
  • uc002iff.2,
  • OTTHUMG00000181806,
  • KIAA0600,
  • HD5
  • identifiers:
  • 10014,
  • ENSG00000108840,
  • HDAC5

Genome feature

Region: gene ? Length: 46899  
Location: 17:44076753-44123651 reverse strand Cyto location: 17q21.31


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Proteins

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SNPs

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Disease

0 Diseases

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Expression

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Other

368 SN Ps

5 Cross References

17 Data Sets

9 Homologues

0 Located Features

97 Rna Seq Results