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Gene : CDH5 Homo sapiens

Name  ? cadherin 5 Cytological Location  16q21
Brief Description  cadherin 5
Description  This gene encodes a classical cadherin of the cadherin superfamily. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classical cadherin by imparting to cells the ability to adhere in a homophilic manner, this protein plays a role in endothelial adherens junction assembly and maintenance. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. [provided by RefSeq, Nov 2015]
  • synonyms:
  • 7B4,
  • uc002eom.5,
  • OTTHUMG00000137495,
  • 7B4,
  • VE-cadherin,
  • HGNC:1764,
  • CD144,
  • CD144,
  • CDH5,
  • NM_001795,
  • cadherin 5, type 2, VE-cadherin (vascular epithelium),
  • cadherin 5, type 2 (vascular endothelium),
  • X79981
  • identifiers:
  • 1003,
  • ENSG00000179776,
  • CDH5

Genome feature

Region: gene ? Length: 38128  
Location: 16:66366657-66404784 Cyto location: 16q21

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



58 SN Ps

5 Cross References

17 Data Sets

26 Homologues

3 Located Features

97 Rna Seq Results