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Gene : APELA Homo sapiens

Name  ? apelin receptor early endogenous ligand Cytological Location  4q32.3
Brief Description  apelin receptor early endogenous ligand
Description  This gene encodes a peptide hormone that binds to the Apelin receptor. The encoded protein is required for heart development in zebrafish and has been shown to maintain self-renewal of human embryonic stem cells through activation of the PI3K/AKT pathway. Experiments in human and mouse cell lines point to additional roles for the encoded protein in angiogenesis and regulation of vascular tone. [provided by RefSeq, Jul 2016]
  • synonyms:
  • APELA,
  • tdl,
  • ELA,
  • NM_001297550,
  • Ende,
  • Ende,
  • ELA,
  • OTTHUMG00000161255,
  • toddler,
  • HGNC:48925,
  • tdl
  • identifiers:
  • 100506013,
  • ENSG00000248329,

Genome feature

Region: gene ? Length: 22041  
Location: 4:164877023-164899063 Cyto location: 4q32.3

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Chromosomal location.

Gene --> GO terms.

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Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



0 Pathways

19 SN Ps

4 Cross References

11 Data Sets

0 Homologues

0 Located Features

97 Rna Seq Results