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Gene : CDH8 Homo sapiens

Name  ? cadherin 8 Cytological Location  16q21
Brief Description  cadherin 8
Description  This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed in brain and is putatively involved in synaptic adhesion, axon outgrowth and guidance. [provided by RefSeq, Jul 2008]
  • synonyms:
  • OTTHUMG00000137493,
  • HGNC:1767,
  • L34060,
  • Nbla04261,
  • cadherin 8, type 2,
  • CDH8,
  • NM_001796,
  • uc002eog.3
  • identifiers:
  • 1006,
  • ENSG00000150394,
  • CDH8

Genome feature

Region: gene ? Length: 396049  
Location: 16:61640398-62036446 reverse strand Cyto location: 16q21


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Genomics

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Proteins

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SNPs

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Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Homology

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Interactions

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Expression

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Other

308 SN Ps

5 Cross References

17 Data Sets

25 Homologues

0 Located Features

97 Rna Seq Results