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Gene : ACTR1B Homo sapiens

Name  ? actin related protein 1B Cytological Location  2q11.2
Brief Description  actin related protein 1B
Description  This gene encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins, which are of equal length and share 90% amino acid identity, are present in a constant ratio of approximately 1:15 in the dynactin complex. [provided by RefSeq, Aug 2008]
  • synonyms:
  • ARP1 actin related protein 1 homolog B,
  • PC3,
  • ARP1 actin-related protein 1 homolog B, centractin beta,
  • Arp1B,
  • uc002syb.3,
  • HGNC:168,
  • ARP1 (actin-related protein 1, yeast) homolog B (centractin beta),
  • CTRN2,
  • ARP1B,
  • X82207,
  • OTTHUMG00000130549,
  • CTRN2,
  • NM_005735,
  • ACTR1B,
  • centractin beta
  • identifiers:
  • 10120,
  • ENSG00000115073,
  • ACTR1B

Genome feature

Region: gene ? Length: 8106  
Location: 2:97655939-97664044 reverse strand Cyto location: 2q11.2

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3756 SN Ps

5 Cross References

15 Data Sets

33 Homologues

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97 Rna Seq Results