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Gene : CELA3A Homo sapiens

Name  ? chymotrypsin like elastase 3A Cytological Location  1p36.12
Brief Description  chymotrypsin like elastase 3A
Description  Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase 3A has little elastolytic activity. Like most of the human elastases, elastase 3A is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. Elastase 3A preferentially cleaves proteins after alanine residues. Elastase 3A may also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1. [provided by RefSeq, Jul 2008]
  • synonyms:
  • uc001bfl.4,
  • ELA3A,
  • CELA3A,
  • NM_005747,
  • ELA3A,
  • elastase 3A, pancreatic,
  • HGNC:15944,
  • protease E,
  • elastase 3A, pancreatic (protease E),
  • ELA3,
  • OTTHUMG00000002755,
  • ELA3,
  • chymotrypsin-like elastase family, member 3A,
  • D00306
  • identifiers:
  • 10136,
  • ENSG00000142789,
  • CELA3A

Genome feature

Region: gene ? Length: 10886  
Location: 1:22001657-22012542 Cyto location: 1p36.12

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


Homologue Displayer


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



0 Pathways

256 SN Ps

5 Cross References

15 Data Sets

4 Homologues

0 Located Features

97 Rna Seq Results