help  | about  | cite  | software

Gene : G3BP1 Homo sapiens

Name  ? G3BP stress granule assembly factor 1 Cytological Location  5q33.1
Brief Description  G3BP stress granule assembly factor 1
Description  This gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]
  • synonyms:
  • NM_005754,
  • HDH-VIII,
  • uc003lum.4,
  • DNA helicase VIII,
  • HDH-VIII,
  • BC006997,
  • HGNC:30292,
  • GTPase activating protein (SH3 domain) binding protein 1,
  • OTTHUMG00000130123,
  • G3BP,
  • G3BP1,
  • Ras-GTPase-activating protein SH3-domain-binding protein,
  • G3BP
  • identifiers:
  • 10146,
  • ENSG00000145907,
  • G3BP1

Genome feature

Region: gene ? Length: 40832  
Location: 5:151771954-151812785 Cyto location: 5q33.1


Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer

Function

Gene Ontology Displayer

0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

Homologue Displayer

Interactions

Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

0 Pathways

3753 SN Ps

5 Cross References

16 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results