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Function
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72 Pathways
- APC/C-mediated degradation of cell cycle proteins,
- DNA Replication,
- Chromosome Maintenance,
- Cellular Senescence,
- G1/S DNA Damage Checkpoints,
- RNA Polymerase II Transcription,
- p53-Dependent G1 DNA Damage Response,
- Disease,
- Signaling by Non-Receptor Tyrosine Kinases,
- G2/M Transition,
- Telomere Maintenance,
- DNA Double-Strand Break Repair,
- G0 and Early G1,
- Mitotic G2-G2/M phases,
- Regulation of TP53 Expression and Degradation,
- CDK-mediated phosphorylation and removal of Cdc6,
- Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes,
- Generic Transcription Pathway,
- p53-Dependent G1/S DNA damage checkpoint,
- Extension of Telomeres,
- Defective binding of RB1 mutants to E2F1,(E2F2, E2F3),
- Cell Cycle, Mitotic,
- Signaling by PTK6,
- DNA Damage/Telomere Stress Induced Senescence,
- Cellular responses to stress,
- Activation of the pre-replicative complex,
- Transcriptional regulation of granulopoiesis,
- Cyclin A:Cdk2-associated events at S phase entry,
- G1 Phase,
- Gene expression (Transcription),
- G2 Phase,
- G1/S Transition,
- Cyclin D associated events in G1,
- Regulation of TP53 Activity through Phosphorylation,
- Developmental Biology,
- Signal Transduction,
- Switching of origins to a post-replicative state,
- Regulation of mitotic cell cycle,
- DNA Repair,
- Synthesis of DNA,
- Meiotic recombination,
- TP53 Regulates Transcription of Cell Cycle Genes,
- Factors involved in megakaryocyte development and platelet production,
- Senescence-Associated Secretory Phenotype (SASP),
- Regulation of TP53 Activity,
- S Phase,
- PTK6 Regulates Cell Cycle,
- Regulation of APC/C activators between G1/S and early anaphase,
- Cyclin A/B1/B2 associated events during G2/M transition,
- Activation of ATR in response to replication stress,
- Telomere Extension By Telomerase,
- Processing of DNA double-strand break ends,
- Cell Cycle Checkpoints,
- SCF(Skp2)-mediated degradation of p27/p21,
- HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA),
- Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects,
- Homology Directed Repair,
- Diseases of mitotic cell cycle,
- G2/M Checkpoints,
- Cyclin E associated events during G1/S transition ,
- TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest,
- Hemostasis,
- Transcriptional Regulation by TP53,
- Cell Cycle,
- Cellular responses to external stimuli,
- Regulation of TP53 Degradation,
- Mitotic G1 phase and G1/S transition,
- Orc1 removal from chromatin,
- DNA Replication Pre-Initiation,
- Aberrant regulation of mitotic cell cycle due to RB1 defects,
- Meiosis,
- Reproduction
Gene --> GO terms.
Gene -> HPO annotation (Human Phenotype Ontology)
Mouse Gene --> Allele [Phenotype]
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Gene --> Chromosomal location.
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Disease
Gene (Hum OR Rat) --> Mouse Allele (Phenotype)
Gene --> Alleles and Disease (clinVar data)
Gene -> HPO annotation (Human Phenotype Ontology)
Mouse Gene --> Allele [Phenotype]
Other
72 Pathways
- APC/C-mediated degradation of cell cycle proteins,
- DNA Replication,
- Chromosome Maintenance,
- Cellular Senescence,
- G1/S DNA Damage Checkpoints,
- RNA Polymerase II Transcription,
- p53-Dependent G1 DNA Damage Response,
- Disease,
- Signaling by Non-Receptor Tyrosine Kinases,
- G2/M Transition,
- Telomere Maintenance,
- DNA Double-Strand Break Repair,
- G0 and Early G1,
- Mitotic G2-G2/M phases,
- Regulation of TP53 Expression and Degradation,
- CDK-mediated phosphorylation and removal of Cdc6,
- Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes,
- Generic Transcription Pathway,
- p53-Dependent G1/S DNA damage checkpoint,
- Extension of Telomeres,
- Defective binding of RB1 mutants to E2F1,(E2F2, E2F3),
- Cell Cycle, Mitotic,
- Signaling by PTK6,
- DNA Damage/Telomere Stress Induced Senescence,
- Cellular responses to stress,
- Activation of the pre-replicative complex,
- Transcriptional regulation of granulopoiesis,
- Cyclin A:Cdk2-associated events at S phase entry,
- G1 Phase,
- Gene expression (Transcription),
- G2 Phase,
- G1/S Transition,
- Cyclin D associated events in G1,
- Regulation of TP53 Activity through Phosphorylation,
- Developmental Biology,
- Signal Transduction,
- Switching of origins to a post-replicative state,
- Regulation of mitotic cell cycle,
- DNA Repair,
- Synthesis of DNA,
- Meiotic recombination,
- TP53 Regulates Transcription of Cell Cycle Genes,
- Factors involved in megakaryocyte development and platelet production,
- Senescence-Associated Secretory Phenotype (SASP),
- Regulation of TP53 Activity,
- S Phase,
- PTK6 Regulates Cell Cycle,
- Regulation of APC/C activators between G1/S and early anaphase,
- Cyclin A/B1/B2 associated events during G2/M transition,
- Activation of ATR in response to replication stress,
- Telomere Extension By Telomerase,
- Processing of DNA double-strand break ends,
- Cell Cycle Checkpoints,
- SCF(Skp2)-mediated degradation of p27/p21,
- HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA),
- Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects,
- Homology Directed Repair,
- Diseases of mitotic cell cycle,
- G2/M Checkpoints,
- Cyclin E associated events during G1/S transition ,
- TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest,
- Hemostasis,
- Transcriptional Regulation by TP53,
- Cell Cycle,
- Cellular responses to external stimuli,
- Regulation of TP53 Degradation,
- Mitotic G1 phase and G1/S transition,
- Orc1 removal from chromatin,
- DNA Replication Pre-Initiation,
- Aberrant regulation of mitotic cell cycle due to RB1 defects,
- Meiosis,
- Reproduction
