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Gene : ADAM10 Homo sapiens

Name  ? ADAM metallopeptidase domain 10 Cytological Location  15q21.3
Brief Description  ADAM metallopeptidase domain 10
Description  Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin. Alternate splicing results in multiple transcript variants encoding different proteins that may undergo similar processing. [provided by RefSeq, Feb 2016]
  • synonyms:
  • HGNC:188,
  • uc002afd.3,
  • CDw156,
  • ADAM10,
  • OTTHUMG00000132633,
  • AD10,
  • AF009615,
  • kuz,
  • a disintegrin and metalloproteinase domain 10,
  • MADM,
  • HsT18717,
  • CD156C,
  • MADM,
  • CD156c,
  • AD18,
  • NM_001110,
  • RAK,
  • HsT18717,
  • kuz
  • identifiers:
  • 102,
  • ENSG00000137845,
  • ADAM10

Genome feature

Region: gene ? Length: 160899  
Location: 15:58588809-58749707 reverse strand Cyto location: 15q21.3

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41 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


2 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



41 Pathways

3753 SN Ps

5 Cross References

20 Data Sets

7 Homologues

0 Located Features

97 Rna Seq Results