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Gene : CDK5 Homo sapiens

Name  ? cyclin dependent kinase 5 Cytological Location  7q36.1
Brief Description  cyclin dependent kinase 5
Description  This gene encodes a proline-directed serine/threonine kinase that is a member of the cyclin-dependent kinase family of proteins. Unlike other members of the family, the protein encoded by this gene does not directly control cell cycle regulation. Instead the protein, which is predominantly expressed at high levels in mammalian postmitotic central nervous system neurons, functions in diverse processes such as synaptic plasticity and neuronal migration through phosphorylation of proteins required for cytoskeletal organization, endocytosis and exocytosis, and apoptosis. In humans, an allelic variant of the gene that results in undetectable levels of the protein has been associated with lethal autosomal recessive lissencephaly-7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015]
  • synonyms:
  • X66364,
  • HGNC:1774,
  • PSSALRE,
  • PSSALRE,
  • uc003wir.3,
  • CDK5,
  • LIS7,
  • NM_001164410,
  • OTTHUMG00000158414
  • identifiers:
  • 1020,
  • ENSG00000164885,
  • CDK5

Genome feature

Region: gene ? Length: 4083  
Location: 7:151053815-151057897 reverse strand Cyto location: 7q36.1


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Gene -> HPO annotation (Human Phenotype Ontology)

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Genomics

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Proteins

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SNPs

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Disease

1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

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Expression

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Other

9 SN Ps

5 Cross References

19 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results