help  | about  | cite  | software

Gene : DENND4A Homo sapiens

Name  ? DENN domain containing 4A Cytological Location  15q22.31
Brief Description  DENN domain containing 4A
description  This gene encodes a DENN domain-containing protein that may function as a guanine nucleotide exchange factor that specifically activates ras-related protein Rab-10. This protein also contains a interferon stimulated response element-binding domain and may be involved in regulating the v-myc avian myelocytomatosis viral (MYC) oncogene. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 8. [provided by RefSeq, Mar 2016]
  • synonyms:
  • HGNC:24321,
  • OTTHUMG00000172635,
  • DENN/MADD domain containing 4A,
  • AF534403,
  • DENND4A,
  • IRLB,
  • uc002aph.4,
  • IRLB,
  • c-myc promoter binding protein,
  • NM_005848
  • identifiers:
  • 10260,
  • ENSG00000174485,

Genome feature

Region: gene ? Length: 137060  
Location: 15:65655234-65792293 reverse strand Cyto location: 15q22.31

Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer


Gene Ontology Displayer

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


Homologue Displayer

Gene --> Orthologues


Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



3756 SN Ps

5 Cross References

16 Data Sets

8 Homologues

0 Located Features

97 Rna Seq Results